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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC6
All Species:
6.67
Human Site:
S398
Identified Species:
13.33
UniProt:
O95255
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95255
NP_001162.4
1503
164906
S398
R
K
V
L
A
L
S
S
G
S
R
K
A
S
A
Chimpanzee
Pan troglodytes
XP_001145351
1247
137800
T263
G
T
F
T
W
V
C
T
P
F
L
V
A
L
C
Rhesus Macaque
Macaca mulatta
XP_001109862
1347
147568
Q363
M
F
L
S
A
C
L
Q
T
L
F
E
Q
Q
N
Dog
Lupus familis
XP_547113
1504
165780
S398
R
K
V
L
V
L
S
S
A
S
R
K
A
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1S7
1498
164770
S401
L
S
S
G
S
R
K
S
S
A
A
G
D
V
V
Rat
Rattus norvegicus
O88269
1502
164977
S401
L
S
S
G
S
R
K
S
S
A
A
G
D
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517193
1537
172363
N424
R
K
A
L
V
I
T
N
S
A
R
K
S
S
T
Chicken
Gallus gallus
Q5F364
1525
170953
N411
R
K
A
L
V
I
T
N
S
A
R
K
T
S
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001341895
1518
169232
N411
R
K
A
L
V
I
T
N
A
A
R
R
T
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
R306
I
R
Q
G
Q
Y
I
R
G
F
D
F
A
R
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LZJ5
1539
172119
G411
K
K
G
L
K
L
T
G
S
A
R
Q
N
H
G
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
N394
Q
K
S
L
V
L
S
N
E
A
S
G
L
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.6
84.9
79.5
N.A.
78.5
78.4
N.A.
45
45.3
N.A.
45.9
N.A.
28.2
N.A.
N.A.
N.A.
Protein Similarity:
100
55.6
86.8
87.3
N.A.
85.8
86
N.A.
63.5
63.2
N.A.
64.1
N.A.
46.9
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
86.6
N.A.
6.6
6.6
N.A.
40
40
N.A.
33.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
86.6
N.A.
20
20
N.A.
73.3
66.6
N.A.
66.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.9
33.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.5
52.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
0
17
0
0
0
17
59
17
0
34
0
17
% A
% Cys:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
9
0
17
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% E
% Phe:
0
9
9
0
0
0
0
0
0
17
9
9
0
0
0
% F
% Gly:
9
0
9
25
0
0
0
9
17
0
0
25
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
9
0
0
0
0
25
9
0
0
0
0
0
0
0
0
% I
% Lys:
9
59
0
0
9
0
17
0
0
0
0
34
0
0
0
% K
% Leu:
17
0
9
59
0
34
9
0
0
9
9
0
9
9
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
34
0
0
0
0
9
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
9
0
9
0
9
0
0
9
0
0
0
9
9
9
0
% Q
% Arg:
42
9
0
0
0
17
0
9
0
0
50
9
0
9
9
% R
% Ser:
0
17
25
9
17
0
25
34
42
17
9
0
9
50
9
% S
% Thr:
0
9
0
9
0
0
34
9
9
0
0
0
17
0
25
% T
% Val:
0
0
17
0
42
9
0
0
0
0
0
9
0
17
17
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _